Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,911 – 2,925 of 3,759 results

2,911

Ambeed Benzyl 3oxocyclobutyl carbama

Benzyl (3-oxocyclobutyl)carbamate, 130369-36-7, 97%

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2,912

Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 10 G

7-Methylisatin is a derivative of Isatin and can be utilized as a molecular block for biochemical assay reagents.

Derivative of Isatin
Can be utilized as a molecular block
For research use only
Store at room temperature for 3 years; in solvent, -80°C for 2 years; -20°C for 1 year
Soluble in DMSO

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2,913

Apexbio Technology LLC STF 31 724741-75-7 50mg

STF 31 (CAS 724741-75-7) is a small-molecule inhibitor targeting glucose transporter 1 (GLUT1) with an IC50 of 1 M By antagonizing GLUT1 STF 31 disrupts glucose uptake selectively impairing survival in VHL-deficient renal cell carcinoma (RCC) models that depend on enhanced glycolysis In vitro STF 31 exhibits selective cytotoxicity toward VHL-deficient RCC4 cells while exerting minimal effects on RCC4/VHL controls In vivo administration of STF 31 analogs retards tumor growth in VHL-deficient RCC xenografts without notable toxicity in mice STF 31 is utilized in research to investigate GLUT1-mediated metabolic dependencies and therapeutic vulnerabilities in cancer and neuroinflammatory models

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2,914

Selleck Chemical LLC FLI-06

FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2 3 M

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2,915

Selleck Chemical LLC Emb-06-A4040-1MG

Emb-06 is a tetravalent CD3 BCMA bispecific antibody in a Fabs-In-Tandem-Ig format with four active antigen-binding sites It targets BCMA on tumor cells and CD3 on T cells promoting immune activation and antitumor activity M W 241 36 kDa

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2,916

Medchemexpress LLC Pomalidomide-amido-C3-COOH | 2162120-77-4 | 99.5% | 387.34 | 100 MG

Pomalidomide-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker used in PROTAC technology.

Synthesized E3 ligase ligand-linker conjugate
Incorporates Pomalidomide-based cereblon ligand
Linker used in PROTAC technology
Intended for research use only
Solid appearance
White to light yellow color
Stable under recommended storage conditions
Used in cancer and cancer targeted therapy research

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2,917

Medchemexpress LLC SBI-553 | 1849603-72-0 | 99.7% | 450.55 | 10 MG

SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM. It induces β-blocking protein recruitment and NTSR1 internalization without stimulating Gq protein activation, IP3 production, or calcium mobilization. In vivo, it alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice. This product is for research use only.

Potent and brain penetrant NTR1 allosteric modulator with an EC50 of 0.34 μM
Induces β-blocking protein recruitment and NTSR1 internalization
Does not stimulate Gq protein activation, IP3 production, or calcium mobilization
Alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice
For research use only

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2,918

Ambeed R 5 S 1 2Dihydroxyethyl 3 4d

(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, 50-81-7, 98%

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2,919

Medchemexpress LLC N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine ethyl ester | 1401089-31-3 | 99.3% | 430.47 | C21H22N2O6S | 50 MG

PACMA 31 is an irreversible small-molecule inhibitor of protein disulfide isomerase (PDI) used for biochemical and cell-based research. It covalently modifies PDI active-site cysteines, has a reported IC50 of about 10 μM, shows tumor-targeting activity in preclinical models, and contains an alkyne group compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.

Irreversible PDI inhibitor that covalently modifies active-site cysteines.
Reported IC50 of approximately 10 μM for PDI activity inhibition.
Demonstrated tumor-targeting activity in preclinical studies.
Contains an alkyne functional group for CuAAC click chemistry applications.
Solid form and high reported purity suitable for research use.

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2,920

Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 1 ML

3,7,4'-Trihydroxyflavone, also known as 5-Deoxykampferol, is a flavonoid compound isolated from the stems of Rhus javanica var. roxburghiana. It exhibits anti-inflammatory and antioxidant properties by scavenging various reactive oxygen species (ROS) and reactive nitrogen species (RNS), and can also cleave DNA in the presence of copper ions.

Isolated from natural sources like Rhus javanica var. roxburghiana.
Functions as an anti-inflammatory agent.
Possesses antioxidant activities.
Capable of scavenging reactive oxygen and nitrogen species.
Can cleave DNA when copper ions are present.

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2,921

Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 50 MG

SKA-31 is a potent potassium channel activator that potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. It is suitable for research use only.

Potent potassium channel activator with specific EC50 values for KCa3.1, KCa2.2, KCa2.1, and KCa2.3.
Potentiates endothelium-derived hyperpolarizing factor response.
Lowers blood pressure.
Activates KCa2/3 channels more potently and selectively than other activators.
Not acutely toxic and has good pharmacokinetic properties.
Stimulates KCa3.1 and KCa2.3 in vascular endothelial cells, increasing acetylcholine-induced endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilation.

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2,922

Ambeed 4Nitroisophthalic acid

4-Nitroisophthalic acid, 4315-09-7, 98%

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2,923

Medchemexpress LLC LM11A-31 dihydrochloride | 1243259-19-9 | 99.9% | 316.27 | 1 ML

LM11A-31 dihydrochloride is a non-peptide modulator of p75NTR (neurotrophin receptor p75) and an orally active, potent antagonist of proNGF (nerve growth factor). This amino acid derivative demonstrates high blood-brain barrier permeability, effectively blocking p75-mediated cell death. It has been shown to reverse cholinergic neurite dystrophy in mouse models of Alzheimer's disease at mid- to late-stage progression.

Non-peptide p75NTR modulator
Orally active and potent proNGF antagonist
Amino acid derivative
High blood-brain barrier permeability
Blocks p75-mediated cell death
Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models

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2,924

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

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2,925

Apexbio Technology LLC R 59-022 93076-89-2 10mg

R 59-022 (CAS 93076-89-2) is a small molecule inhibitor of diacylglycerol kinase (DGK) demonstrating an IC50 of 2 8 M for DGK activity By inhibiting the conversion of 1-oleoyl-2-acetylglycerol to phosphatidic acid R 59-022 modulates diacylglycerol signaling pathways The compound also exhibits antagonistic effects at serotonin (5-HT) receptors and can induce activation of protein kinase C (PKC) In cellular studies R 59-022 enhances thrombin-induced diacylglycerol accumulation in platelets and suppresses phosphatidic acid formation in neutrophils It serves as a valuable tool for investigating DGK-mediated processes and signal transduction mechanisms

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Quinolines and derivatives

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Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC STF 31 724741-75-7 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pomalidomide-amido-C3-COOH | 2162120-77-4 | 99.5% | 387.34 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SBI-553 | 1849603-72-0 | 99.7% | 450.55 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine ethyl ester | 1401089-31-3 | 99.3% | 430.47 | C21H22N2O6S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 dihydrochloride | 1243259-19-9 | 99.9% | 316.27 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC R 59-022 93076-89-2 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More